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Design, synthesis and evaluation of inhibitors of the SARS-CoV-2 nsp3 macrodomain.
Sherrill, Lavinia M; Joya, Elva E; Walker, AnnMarie; Roy, Anuradha; Alhammad, Yousef M; Atobatele, Moriama; Wazir, Sarah; Abbas, George; Keane, Patrick; Zhuo, Junlin; Leung, Anthony K L; Johnson, David K; Lehtiö, Lari; Fehr, Anthony R; Ferraris, Dana.
Afiliação
  • Sherrill LM; McDaniel College, Department of Chemistry, 2 College Hill, Westminster, MD 21157, USA.
  • Joya EE; McDaniel College, Department of Chemistry, 2 College Hill, Westminster, MD 21157, USA.
  • Walker A; McDaniel College, Department of Chemistry, 2 College Hill, Westminster, MD 21157, USA.
  • Roy A; Infectious Disease Assay Development Laboratory/HTS, University of Kansas, Lawrence, KS 66047, USA.
  • Alhammad YM; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, USA.
  • Atobatele M; Infectious Disease Assay Development Laboratory/HTS, University of Kansas, Lawrence, KS 66047, USA.
  • Wazir S; Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Oulu, Finland.
  • Abbas G; McDaniel College, Department of Chemistry, 2 College Hill, Westminster, MD 21157, USA.
  • Keane P; McDaniel College, Department of Chemistry, 2 College Hill, Westminster, MD 21157, USA.
  • Zhuo J; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Leung AKL; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Oncology, McKusick-Nathans Department of Genetic Medicine and Department of Molecular Biology and Genetics, School of Medicine, Johns Hopkins Univers
  • Johnson DK; Molecular Graphics and Modeling Laboratory and the Computational Chemical Biology Core, University of Kansas, Lawrence, KS 66047, USA.
  • Lehtiö L; Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Oulu, Finland.
  • Fehr AR; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, USA. Electronic address: arfehr@ku.edu.
  • Ferraris D; McDaniel College, Department of Chemistry, 2 College Hill, Westminster, MD 21157, USA. Electronic address: dferraris@mcdaniel.edu.
Bioorg Med Chem ; 67: 116788, 2022 08 01.
Article em En | MEDLINE | ID: mdl-35597097
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / Tratamento Farmacológico da COVID-19 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / Tratamento Farmacológico da COVID-19 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article