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Characterization of effective phytochemicals in traditional Chinese medicine by mass spectrometry.
Chen, Chung-Yu; Li, Yen-Hsien; Li, Zuguang; Lee, Maw-Rong.
Afiliação
  • Chen CY; Research Center for Cancer Biology, China Medical University, Taichung, Taiwan, ROC.
  • Li YH; Department of Chemistry, National Chung Hsing University, Taichung, Taiwan, ROC.
  • Li Z; Department of Chemistry, National Chung Hsing University, Taichung, Taiwan, ROC.
  • Lee MR; College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, People's Republic of China.
Mass Spectrom Rev ; 42(5): 1808-1827, 2023.
Article em En | MEDLINE | ID: mdl-35638257
Traditional Chinese medicines (TCMs) have been widely used in clinical and healthcare applications around the world. The characterization of the phytochemical components in TCMs is very important for studying the therapeutic mechanism of TCMs. In the analysis process, sample preparation and instrument analysis are key steps to improve analysis performance and accuracy. In recent years, chromatography combined with mass spectrometry (MS) has been widely used for the separation and detection of trace components in complex TCM samples. This article reviews various sample preparation techniques and chromatography-MS techniques, including the application of gas chromatography-MS and liquid chromatography-MS and other MS techniques in the characterization of phytochemicals in TCM materials and Chinese medicine products. This article also describes a new ambient ionization MS method for rapid and high-throughput analysis of TCM components.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article