Your browser doesn't support javascript.
loading
Pre-hospital treatment with crushed versus integral tablets of prasugrel in patients presenting with ST-Segment Elevation Myocardial Infarction-1-year follow-up results of the COMPARE CRUSH trial.
Vogel, Rosanne F; Delewi, Ronak; Wilschut, Jeroen M; Lemmert, Miguel E; Diletti, Roberto; van Vliet, Ria; van der Waarden, Nancy W P L; Nuis, Rutger-Jan; Paradies, Valeria; Alexopoulos, Dimitrios; Zijlstra, Felix; Montalescot, Gilles; Angiolillo, Dominick J; Krucoff, Mitchell W; Smits, Pieter C; Van Mieghem, Nicolas M; Vlachojannis, Georgios J.
Afiliação
  • Vogel RF; Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands; Department of Cardiology, Amsterdam UMC location AMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Delewi R; Department of Cardiology, Amsterdam UMC location AMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Wilschut JM; Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Lemmert ME; Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Cardiology, Isala Hospital, Zwolle, The Netherlands.
  • Diletti R; Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • van Vliet R; Department of Cardiology, Maasstad Hospital, Rotterdam, The Netherlands.
  • van der Waarden NWPL; AmbulanceZorg Rotterdam-Rijnmond, Rotterdam, Barendrecht, The Netherlands.
  • Nuis RJ; Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Paradies V; Department of Cardiology, Maasstad Hospital, Rotterdam, The Netherlands.
  • Alexopoulos D; Department of Cardiology, National and Kapodistrian University of Athens Medical School, Attikon University Hospital, Athens, Greece.
  • Zijlstra F; Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Montalescot G; Sorbonne University, ACTION group, Groupe Hospitalier Pitie-Salpetriere Hospital (AP-HP), Paris, France.
  • Angiolillo DJ; Department of Cardiology, University of Florida College of Medicine, Jacksonville, FL.
  • Krucoff MW; Department of Cardiology, Duke University Medical Center, Durham, NC.
  • Smits PC; Department of Cardiology, Maasstad Hospital, Rotterdam, The Netherlands.
  • Van Mieghem NM; Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Vlachojannis GJ; Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands; Department of Cardiology, Maasstad Hospital, Rotterdam, The Netherlands. Electronic address: g.vlachojannis@umcutrecht.nl.
Am Heart J ; 252: 26-30, 2022 10.
Article em En | MEDLINE | ID: mdl-35671829
ABSTRACT
The present research letter reports the 1-year clinical outcomes of the randomized COMPARE CRUSH trial, which allocated STEMI patients at first medical contact in the ambulance to receive either crushed or integral tablets of prasugrel loading dose. This trial aimed to investigate whether early enhanced antiplatelet effect constituted by the crushed potent oral P2Y12 inhibitor prasugrel could lead to improved early myocardial reperfusion and clinical outcomes.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Serviços Médicos de Emergência / Intervenção Coronária Percutânea / Infarto do Miocárdio com Supradesnível do Segmento ST Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Serviços Médicos de Emergência / Intervenção Coronária Percutânea / Infarto do Miocárdio com Supradesnível do Segmento ST Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article