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Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.
Peng, Ting; He, Yujiao; Wang, Tao; Yu, Jialing; Ma, Xiaofang; Zhou, Zongyuan; Sheng, Yuwen; Li, Lingyu; Peng, Huipan; Li, Sheng; Zou, Jiawei; Yuan, Yi; Zhao, Yongyun; Shi, Hailong; Li, Fu; Liu, Wanli; Hu, Kaifeng; Lu, Xiaoxia; Zhang, Guolin; Wang, Fei.
Afiliação
  • Peng T; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
  • He Y; Antibiotics Research and Re-Evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610052, China.
  • Wang T; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Yu J; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
  • Ma X; Antibiotics Research and Re-Evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610052, China.
  • Zhou Z; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
  • Sheng Y; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
  • Li L; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Peng H; Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
  • Li S; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
  • Zou J; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Yuan Y; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
  • Zhao Y; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Shi H; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
  • Li F; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Liu W; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
  • Hu K; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
  • Lu X; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
  • Zhang G; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
  • Wang F; Center for Natural Products Research, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
J Med Chem ; 65(16): 11010-11033, 2022 08 25.
Article em En | MEDLINE | ID: mdl-35695407

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / MicroRNAs / Ribonuclease III / RNA Helicases DEAD-box / Coativadores de Receptor Nuclear / Neoplasias Hepáticas Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / MicroRNAs / Ribonuclease III / RNA Helicases DEAD-box / Coativadores de Receptor Nuclear / Neoplasias Hepáticas Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article