Interpreting protein variant effects with computational predictors and deep mutational scanning.

Livesey, Benjamin J; Marsh, Joseph A

Livesey, Benjamin J; Marsh, Joseph A.

Afiliação

Livesey BJ; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh EH4 2XU, UK.
Marsh JA; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh EH4 2XU, UK.

Dis Model Mech ; 15(6)2022 06 01.

Article em En | MEDLINE | ID: mdl-35736673

Assuntos

Biologia Computacional; Biologia Computacional/métodos; Mutação/genética

Palavras-chave

Benchmarking; Circularity; Deep mutational scan; Machine learning; Multiplexed assay of variant effect; Variant effect predictor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biologia Computacional Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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