Maternal obesity induces liver lipid accumulation of offspring through the lncRNA Lockd/mTOR autophagy pathway.

Chen, Rui; Yang, Hongguang; Song, Yong; Yu, Hongjie; Zhang, Minzhe; Rao, Weiming; Wang, Yaxu; Xiao, Xiaoyue; Chen, Qiutong; He, Qiqiang

Chen, Rui; Yang, Hongguang; Song, Yong; Yu, Hongjie; Zhang, Minzhe; Rao, Weiming; Wang, Yaxu; Xiao, Xiaoyue; Chen, Qiutong; He, Qiqiang.

Afiliação

Chen R; School of Health Sciences, Wuhan University, Wuhan, China.
Yang H; School of Health Sciences, Wuhan University, Wuhan, China.
Song Y; Hubei Provincial Center for Disease Control and Prevention, Wuhan, China.
Yu H; School of Health Sciences, Wuhan University, Wuhan, China.
Zhang M; School of Health Sciences, Wuhan University, Wuhan, China.
Rao W; School of Health Sciences, Wuhan University, Wuhan, China.
Wang Y; School of Health Sciences, Wuhan University, Wuhan, China.
Xiao X; School of Health Sciences, Wuhan University, Wuhan, China.
Chen Q; College of Language Intelligence, Sichuan International Studies University, Chongqing, China.
He Q; Wuhan University Shenzhen Research Institute, Shenzhen, China. heqiqiang@gmail.com.

Mol Genet Genomics ; 297(5): 1277-1287, 2022 Sep.

Article em En | MEDLINE | ID: mdl-35759023

Assuntos

Obesidade Materna; RNA Longo não Codificante; Animais; Autofagia; Feminino; Humanos; Metabolismo dos Lipídeos; Lipídeos; Fígado; Camundongos; Camundongos Endogâmicos C57BL; Gravidez; Sirolimo; Serina-Treonina Quinases TOR

Palavras-chave

Autophagy; Lipid metabolism; LncRNA; Maternal obesity; Offspring

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Longo não Codificante / Obesidade Materna Limite: Animals / Female / Humans / Pregnancy Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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