Baloxavir Marboxil Shows Anomalous Conversion of Crystal Forms from Stable to Metastable through Formation of Specific Solvate Form.

Ueda, Hiroshi; Osaki, Hiromi; Miyano, Tetsuya

Ueda, Hiroshi; Osaki, Hiromi; Miyano, Tetsuya.

Afiliação

Ueda H; Physical Chemistry, Laboratory for Medicinal Chemistry Research, Shionogi & Co., Ltd., Osaka, 561-0825, Japan. Electronic address: hiroshi.ueda@shionogi.co.jp.
Osaki H; Bioanalysis, Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd., Osaka, 561-0825, Japan.
Miyano T; Physical Chemistry, Laboratory for Medicinal Chemistry Research, Shionogi & Co., Ltd., Osaka, 561-0825, Japan.

J Pharm Sci ; 112(1): 158-165, 2023 01.

Article em En | MEDLINE | ID: mdl-35835185

Assuntos

Dibenzotiepinas; Solventes/química; Água/química; Acetonitrilas

Palavras-chave

Baloxavir marboxil; Crystal engineering; Polymorphs; Solid state (13)C-nuclear magnetic resonance; Solvate form; X-ray powder diffraction

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dibenzotiepinas Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dibenzotiepinas Idioma: En Ano de publicação: 2023 Tipo de documento: Article