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Safety and immunogenicity of a simian-adenovirus-vectored rabies vaccine: an open-label, non-randomised, dose-escalation, first-in-human, single-centre, phase 1 clinical trial.
Jenkin, Daniel; Ritchie, Adam J; Aboagye, Jeremy; Fedosyuk, Sofiya; Thorley, Luke; Provstgaad-Morys, Samuel; Sanders, Helen; Bellamy, Duncan; Makinson, Rebecca; Xiang, Zhi Quan; Bolam, Emma; Tarrant, Richard; Ramos Lopez, Fernando; Platt, Abigail; Poulton, Ian; Green, Catherine; Ertl, Hildegund C J; Ewer, Katie J; Douglas, Alexander D.
Afiliação
  • Jenkin D; Jenner Institute, University of Oxford, Oxford, UK; Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, University of Oxford, Oxford, UK.
  • Ritchie AJ; Jenner Institute, University of Oxford, Oxford, UK.
  • Aboagye J; Jenner Institute, University of Oxford, Oxford, UK.
  • Fedosyuk S; Jenner Institute, University of Oxford, Oxford, UK.
  • Thorley L; Jenner Institute, University of Oxford, Oxford, UK.
  • Provstgaad-Morys S; Jenner Institute, University of Oxford, Oxford, UK.
  • Sanders H; Jenner Institute, University of Oxford, Oxford, UK.
  • Bellamy D; Jenner Institute, University of Oxford, Oxford, UK.
  • Makinson R; Jenner Institute, University of Oxford, Oxford, UK.
  • Xiang ZQ; Wistar Institute of Anatomy & Biology, Philadelphia, PA, USA.
  • Bolam E; Clinical Biomanufacturing Facility, University of Oxford, Oxford, UK.
  • Tarrant R; Clinical Biomanufacturing Facility, University of Oxford, Oxford, UK.
  • Ramos Lopez F; Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, University of Oxford, Oxford, UK.
  • Platt A; Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, University of Oxford, Oxford, UK.
  • Poulton I; Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, University of Oxford, Oxford, UK.
  • Green C; Clinical Biomanufacturing Facility, University of Oxford, Oxford, UK.
  • Ertl HCJ; Wistar Institute of Anatomy & Biology, Philadelphia, PA, USA.
  • Ewer KJ; Jenner Institute, University of Oxford, Oxford, UK.
  • Douglas AD; Jenner Institute, University of Oxford, Oxford, UK. Electronic address: sandy.douglas@ndm.ox.ac.uk.
Lancet Microbe ; 3(9): e663-e671, 2022 09.
Article em En | MEDLINE | ID: mdl-35907430
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Raiva / Vacina Antirrábica / Adenovirus dos Símios Tipo de estudo: Clinical_trials Limite: Adult / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Raiva / Vacina Antirrábica / Adenovirus dos Símios Tipo de estudo: Clinical_trials Limite: Adult / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article