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Palladium Nanoparticles Synthesized by Laser Ablation in Liquids for Antimicrobial Applications.
Fernández-Arias, Mónica; Vilas, Ana M; Boutinguiza, Mohamed; Rodríguez, Daniel; Arias-González, Felipe; Pou-Álvarez, Pablo; Riveiro, Antonio; Gil, Javier; Pou, Juan.
Afiliação
  • Fernández-Arias M; LaserON Research Group, CINTECX, School of Engineering, University of Vigo, Lagoas-Marcosende, E-36310 Vigo, Spain.
  • Vilas AM; LaserON Research Group, CINTECX, School of Engineering, University of Vigo, Lagoas-Marcosende, E-36310 Vigo, Spain.
  • Boutinguiza M; LaserON Research Group, CINTECX, School of Engineering, University of Vigo, Lagoas-Marcosende, E-36310 Vigo, Spain.
  • Rodríguez D; Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, E-36310 Vigo, Spain.
  • Arias-González F; Biomaterials, Biomechanics and Tissue Engineering Group, Materials Science and Metallurgical Engineering Department, UPC-Barcelona TECH, 08930 Barcelona, Spain.
  • Pou-Álvarez P; School of Dentistry, Universitat Internacional de Catalunya, 08017 Barcelona, Spain.
  • Riveiro A; LaserON Research Group, CINTECX, School of Engineering, University of Vigo, Lagoas-Marcosende, E-36310 Vigo, Spain.
  • Gil J; LaserON Research Group, CINTECX, School of Engineering, University of Vigo, Lagoas-Marcosende, E-36310 Vigo, Spain.
  • Pou J; Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, E-36310 Vigo, Spain.
Nanomaterials (Basel) ; 12(15)2022 Jul 29.
Article em En | MEDLINE | ID: mdl-35957051
ABSTRACT
Antibiotic resistance is a leading cause of death worldwide. In this paper, we explore new alternatives in the treatment of infections. Noble metal nanoparticles could help to mitigate this problem. In this work, palladium nanoparticles were synthesized by laser ablation in order to explore their antimicrobial capacity. To obtain palladium nanoparticles, a palladium plate immersed in water, or methanol, was ablated, using two pulsed lasers that emit radiation with wavelengths of 532 nm and 1064 nm, respectively. Pure Pd-NPs with crystalline microstructure and rounded shape were obtained. The nanoparticles' size is more homogeneous if the laser wavelength is 532 nm, and it decreases when methanol is used as solvent, reaching mean diameters smaller than 6 nm. With the objective of studying antimicrobial activity against Staphylococcus aureus, the Pd-NPs were immobilized on the surface of titanium discs. The release of palladium ions was recorded during the first seven days, and the cytotoxicity of the immobilized NPs was also tested with L929 mouse fibroblast cell line. Palladium nanoparticles synthesized by means of the infrared laser in methanol showed a strong inhibitory effect on S. aureus and good cytocompatibility, with no toxic effect on fibroblast cells.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article