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Anti-cancer and immunomodulatory evaluation of new nicotinamide derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: in vitro and in silico studies.
Yousef, Reda G; Elwan, Alaa; Gobaara, Ibraheem M M; Mehany, Ahmed B M; Eldehna, Wagdy M; El-Metwally, Souad A; A Alsfouk, Bshra; Elkaeed, Eslam B; Metwaly, Ahmed M; Eissa, Ibrahim H.
Afiliação
  • Yousef RG; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
  • Elwan A; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
  • Gobaara IMM; Zoology Department, Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt.
  • Mehany ABM; Zoology Department, Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt.
  • Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
  • El-Metwally SA; Department of Basic Science, Higher Technological institute, 10th of Ramadan City, Egypt.
  • A Alsfouk B; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
  • Elkaeed EB; Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi Arabia.
  • Metwaly AM; Pharmacognosy and Medicinal Plants Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
  • Eissa IH; Biopharmaceutical Products Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria, Egypt.
J Enzyme Inhib Med Chem ; 37(1): 2206-2222, 2022 Dec.
Article em En | MEDLINE | ID: mdl-35980113
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor 2 de Fatores de Crescimento do Endotélio Vascular / Antineoplásicos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor 2 de Fatores de Crescimento do Endotélio Vascular / Antineoplásicos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article