Your browser doesn't support javascript.
loading
Camels' biological fluids contained nanobodies: promising avenue in cancer therapy.
Al-Numair, Nouf S; Theyab, Abdulrahman; Alzahrani, Faisal; Shams, Anwar M; Al-Anazi, Ibrahim O; Oyouni, Atif Abdulwahab A; Al-Amer, Osama M; Mavromatis, Charalampos; Saadeldin, Islam M; Abdali, Wed A; Hawsawi, Yousef M.
Afiliação
  • Al-Numair NS; Center of Genomic Medicine, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
  • Theyab A; College of Medicine, Alfaisal University, P.O. Box 50927, Riyadh, 11533, Saudi Arabia.
  • Alzahrani F; Department of Laboratory & Blood Bank, Security Forces Hospital, P.O. Box 14799, Mecca, 21955, Saudi Arabia.
  • Shams AM; College of Medicine, Al-Faisal University, P.O. Box 50927, Riyadh, 11533, Saudi Arabia.
  • Al-Anazi IO; Department of Biochemistry, Faculty of Science, Embryonic Stem Cells Unit, King Fahad Medical Center, King Abdulaziz University, Jeddah, Saudi Arabia.
  • Oyouni AAA; Centre of Artificial Intelligence in Precision Medicines (CAIPM), King Abdulaziz University, Jeddah, Saudi Arabia.
  • Al-Amer OM; Department of Pharmacology, College of Medicine, Taif University, P.O. BOX 11099, Taif, 21944, Saudi Arabia.
  • Mavromatis C; The National Center for Genomic Technology, King Abdulaziz City for Science and Technology, P.O Box 6086, Riyadh, 11442, Saudi Arabia.
  • Saadeldin IM; Department of Biology, Faculty of Sciences, University of Tabuk, Tabuk, Saudi Arabia.
  • Abdali WA; Genome and Biotechnology Unit, Faculty of Sciences, University of Tabuk, Tabuk, Saudi Arabia.
  • Hawsawi YM; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk, Saudi Arabia.
Cancer Cell Int ; 22(1): 279, 2022 Sep 07.
Article em En | MEDLINE | ID: mdl-36071488
ABSTRACT
Cancer is a major health concern and accounts for one of the main causes of death worldwide. Innovative strategies are needed to aid in the diagnosis and treatment of different types of cancers. Recently, there has been an evolving interest in utilizing nanobodies of camel origin as therapeutic tools against cancer. Nanotechnology uses nanobodies an emerging attractive field that provides promises to researchers in advancing different scientific sectors including medicine and oncology. Nanobodies are characteristically small-sized biologics featured with the ability for deep tissue penetration and dissemination and harbour high stability at high pH and temperatures. The current review highlights the potential use of nanobodies that are naturally secreted in camels' biological fluids, both milk and urine, in the development of nanotechnology-based therapy for treating different typesQuery of cancers and other diseases. Moreover, the role of nano proteomics in the invention of novel therapeutic agents specifically used for cancer intervention is also illustrated.
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article