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Clinicopathologic Features and Treatment of CD10-Positive Mantle Cell Lymphoma: A Case Report and Review of Literature.
Hino, Christopher; Pham, Bryan; Gray, Austin L; Wang, Jun; Castillo, Dan Ran; Akhtari, Mojtaba; Liu, Yan.
Afiliação
  • Hino C; Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, United States.
  • Pham B; Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, United States.
  • Gray AL; Department of Pathology, Loma Linda University, Loma Linda, CA, United States.
  • Wang J; Department of Pathology, Loma Linda University, Loma Linda, CA, United States.
  • Castillo DR; Department of Oncology/Hematology, Loma Linda University, Loma Linda, CA, United States.
  • Akhtari M; Department of Oncology/Hematology, Loma Linda University, Loma Linda, CA, United States.
  • Liu Y; Department of Pathology, Loma Linda University, Loma Linda, CA, United States.
Pathol Oncol Res ; 28: 1610588, 2022.
Article em En | MEDLINE | ID: mdl-36091937
ABSTRACT
Mantle cell lymphoma (MCL) is a rare and aggressive non-Hodgkin's B cell lymphoma characterized by the translocation t(11;14) (q13;32) and overexpression of CCND1. MCL is immunophenotypically identified as CD20+, CD5+, CyclinD1+, CD43+, CD10-, BCL6-, and CD23-. It is often distinguished from B cell lymphomas of germinal center cell origin by the absence of CD10 expression. Here we report the unique clinicopathologic features of a patient with CD10+ MCL with gastrointestinal involvement and review current literature identifying this unique immunophenotype.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfoma de Células B / Linfoma de Célula do Manto Tipo de estudo: Prognostic_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfoma de Células B / Linfoma de Célula do Manto Tipo de estudo: Prognostic_studies Limite: Adult / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article