PAX5 P80R-mutated B-cell acute lymphoblastic leukemia with transformation to histiocytic sarcoma: clonal evolution assessment using NGS-based immunoglobulin clonality and mutation analysis.

Kroeze, Leonie I; Scheijen, B; Hebeda, K M; Rijntjes, J; Luijks, J A C W; Evers, D; Hobo, W; Groenen, P J T A; van den Brand, M

Kroeze, Leonie I; Scheijen, B; Hebeda, K M; Rijntjes, J; Luijks, J A C W; Evers, D; Hobo, W; Groenen, P J T A; van den Brand, M.

Afiliação

Kroeze LI; Department of Pathology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA, Nijmegen, the Netherlands. leonie.kroeze@radboudumc.nl.
Scheijen B; Department of Pathology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA, Nijmegen, the Netherlands.
Hebeda KM; Radboud Institute for Molecular Life Sciences, Nijmegen, the Netherlands.
Rijntjes J; Department of Pathology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA, Nijmegen, the Netherlands.
Luijks JACW; Department of Pathology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA, Nijmegen, the Netherlands.
Evers D; Department of Pathology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA, Nijmegen, the Netherlands.
Hobo W; Department of Hematology, Radboud University Medical Center, Nijmegen, the Netherlands.
Groenen PJTA; Department of Laboratory Medicine - Laboratory of Hematology, Radboud University Medical Center, Nijmegen, the Netherlands.
van den Brand M; Department of Pathology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA, Nijmegen, the Netherlands.

Virchows Arch ; 483(1): 105-110, 2023 Jul.

Article em En | MEDLINE | ID: mdl-36241730

Assuntos

Linfoma de Burkitt; Sarcoma Histiocítico; Leucemia-Linfoma Linfoblástico de Células Precursoras; Humanos; Sarcoma Histiocítico/genética; Sarcoma Histiocítico/patologia; Imunoglobulinas/genética; Rearranjo Gênico; Linfoma de Burkitt/genética; Sequenciamento de Nucleotídeos em Larga Escala/métodos; Leucemia-Linfoma Linfoblástico de Células Precursoras/genética; Fator de Transcrição PAX5/genética

Palavras-chave

Acute lymphoblastic leukemia; Clonal evolution; Clonality analysis; Histiocytic sarcoma; Transformation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfoma de Burkitt / Sarcoma Histiocítico / Leucemia-Linfoma Linfoblástico de Células Precursoras Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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