The single cell transcriptional landscape of esophageal adenocarcinoma and its modulation by neoadjuvant chemotherapy.

Croft, Wayne; Evans, Richard P T; Pearce, Hayden; Elshafie, Mona; Griffiths, Ewen A; Moss, Paul

Croft, Wayne; Evans, Richard P T; Pearce, Hayden; Elshafie, Mona; Griffiths, Ewen A; Moss, Paul.

Afiliação

Croft W; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Evans RPT; Centre for Computational Biology, University of Birmingham, Birmingham, UK.
Pearce H; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Elshafie M; University Hospitals Foundation Trust, Edgbaston, Birmingham, UK.
Griffiths EA; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Moss P; University Hospitals Foundation Trust, Edgbaston, Birmingham, UK.

Mol Cancer ; 21(1): 200, 2022 10 17.

Article em En | MEDLINE | ID: mdl-36253784

Assuntos

Adenocarcinoma; Neoplasias Esofágicas; Adenocarcinoma/tratamento farmacológico; Adenocarcinoma/genética; Células Endoteliais/patologia; Neoplasias Esofágicas/tratamento farmacológico; Neoplasias Esofágicas/genética; Humanos; Inibidores de Checkpoint Imunológico; Terapia Neoadjuvante; Microambiente Tumoral/genética

Palavras-chave

Cancer-associated fibroblast; Esophageal adenocarcinoma; Plasmacytoid dendritic cell; Regulatory T cell; scRNA-Seq

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Adenocarcinoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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