Tetramer-aided sorting and single-cell RNA sequencing facilitate transcriptional profiling of antigen-specific CD8+ T cells.

Rajasekaran, Kamalakannan; Guan, Xiangnan; Tafazzol, Alireza; Hamidi, Habib; Darwish, Martine; Yadav, Mahesh

Rajasekaran, Kamalakannan; Guan, Xiangnan; Tafazzol, Alireza; Hamidi, Habib; Darwish, Martine; Yadav, Mahesh.

Afiliação

Rajasekaran K; Genentech, 1 DNA way, South San Francisco, CA 94080, USA. Electronic address: rajasek1@gene.com.
Guan X; Genentech, 1 DNA way, South San Francisco, CA 94080, USA.
Tafazzol A; Genentech, 1 DNA way, South San Francisco, CA 94080, USA.
Hamidi H; Genentech, 1 DNA way, South San Francisco, CA 94080, USA.
Darwish M; Genentech, 1 DNA way, South San Francisco, CA 94080, USA.
Yadav M; Genentech, 1 DNA way, South San Francisco, CA 94080, USA. Electronic address: yadavm2@gene.com.

Transl Oncol ; 27: 101559, 2023 Jan.

Article em En | MEDLINE | ID: mdl-36279715

Palavras-chave

Antigen-specific response gene signature; CMV pp65-specific CD8+ T cells; Cancer immunotherapy; FACS sorting; Single-cell RNA sequencing; TCR analysis; pMHC Tetramers

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article