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Safety, pharmacokinetics and antiviral activity of ABI-H2158, a hepatitis B virus core inhibitor: A randomized, placebo-controlled phase 1 study.
Agarwal, Kosh; Xu, Jia; Gane, Edward J; Nguyen, Tuan T; Ding, Yanhua; Knox, Steven J; Alves, Katia; Evanchik, Marc; Zomorodi, Katie; Ma, Julie; Yan, Ran; Huang, Qi; Colonno, Richard; Stamm, Luisa M; Hassanein, Tarek I; Kim, Dong Joon; Lim, Young-Suk; Yuen, Man-Fung.
Afiliação
  • Agarwal K; Institute of Liver Studies, King's College Hospital, London, UK.
  • Xu J; Phase 1 Clinical Trials Unit, The First Hospital of Jilin University, Jilin, China.
  • Gane EJ; University of Auckland, Auckland, New Zealand.
  • Nguyen TT; T Nguyen Research and Education, Inc., San Diego, California, USA.
  • Ding Y; Phase 1 Clinical Trials Unit, The First Hospital of Jilin University, Jilin, China.
  • Knox SJ; Assembly Biosciences, Inc., South San Francisco, California, USA.
  • Alves K; Assembly Biosciences, Inc., South San Francisco, California, USA.
  • Evanchik M; Assembly Biosciences, Inc., South San Francisco, California, USA.
  • Zomorodi K; Assembly Biosciences, Inc., South San Francisco, California, USA.
  • Ma J; Assembly Biosciences, Inc., South San Francisco, California, USA.
  • Yan R; Assembly Biosciences, Inc., South San Francisco, California, USA.
  • Huang Q; Assembly Biosciences, Inc., South San Francisco, California, USA.
  • Colonno R; Assembly Biosciences, Inc., South San Francisco, California, USA.
  • Stamm LM; Assembly Biosciences, Inc., South San Francisco, California, USA.
  • Hassanein TI; Southern California Research Center, Coronado, California, USA.
  • Kim DJ; Hallym University Chuncheon Sacred Heart Hospital, Chuncheon, South Korea.
  • Lim YS; Asan Medical Centre, University of Ulsan College of Medicine, Seoul, South Korea.
  • Yuen MF; Department of Medicine, University of Hong Kong, Hong Kong, Hong Kong.
J Viral Hepat ; 30(3): 209-222, 2023 03.
Article em En | MEDLINE | ID: mdl-36302125
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Hepatite B Crônica Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Hepatite B Crônica Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article