[Precision oncology from a proteogenomics perspective].
Sheng Wu Gong Cheng Xue Bao
; 38(10): 3616-3627, 2022 Oct 25.
Article
em Zh
| MEDLINE
| ID: mdl-36305397
ABSTRACT
Cancer is a heterogeneous disease with complex mechanisms that requires targeted precision medicine strategies. The growth of precision medicine is indispensable from the rapid development of genomics. However, genomics has certain limitations in molecular phenotype analysis, proteogenomics thus arose at the right time. Proteogenomics is the merging of proteomics and genomics. This review describes the limitations of genomic analysis and highlights the importance of proteogenomics to re-understand precision oncology from a proteogenomic perspective. In addition, the application of proteogenomics in precision oncology is briefly introduced, the related public data projects are described, and finally, the challenges that need to be addressed at this stage are proposed.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteogenômica
/
Neoplasias
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2022
Tipo de documento:
Article