Effects of hypoxia on antigen presentation and T cell-based immune recognition of HPV16-transformed cells.

Mohan, Nitya; Wellach, Kathrin; Özerdem, Ceren; Veits, Nisha; Förster, Jonas D; Foehr, Sophia; Bonsack, Maria; Riemer, Angelika B

Mohan, Nitya; Wellach, Kathrin; Özerdem, Ceren; Veits, Nisha; Förster, Jonas D; Foehr, Sophia; Bonsack, Maria; Riemer, Angelika B.

Afiliação

Mohan N; Immunotherapy and Immunoprevention, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Wellach K; Molecular Vaccine Design, German Center for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany.
Özerdem C; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
Veits N; Immunotherapy and Immunoprevention, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Förster JD; Molecular Vaccine Design, German Center for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany.
Foehr S; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
Bonsack M; Immunotherapy and Immunoprevention, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Riemer AB; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.

Front Immunol ; 13: 918528, 2022.

Article em En | MEDLINE | ID: mdl-36341354

Assuntos

Infecções por Papillomavirus; Neoplasias do Colo do Útero; Feminino; Humanos; Papillomavirus Humano 16; Apresentação de Antígeno; Epitopos de Linfócito T; Papillomaviridae; Antígenos de Histocompatibilidade Classe I; Hipóxia; Microambiente Tumoral

Palavras-chave

Hypoxia; antigen processing and presentation machinery (APM); cytotoxic T cells; human papillomavirus (HPV); tumor microenvironment (TME)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias do Colo do Útero / Infecções por Papillomavirus Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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