Regulation of DNA-PK activity promotes the progression of TNBC via enhancing the immunosuppressive function of myeloid-derived suppressor cells.

Han, Jiawen; Wan, Minjie; Ma, Zhanchuan; Yi, Huanfa

Han, Jiawen; Wan, Minjie; Ma, Zhanchuan; Yi, Huanfa.

Afiliação

Han J; Central Laboratory, The First Hospital of Jilin University, Changchun, China.
Wan M; Key Laboratory of Organ Regeneration and Transplantation Ministry of Education, Changchun, China.
Ma Z; Central Laboratory, The First Hospital of Jilin University, Changchun, China.
Yi H; Department of Hepatology, The First Hospital of Jilin University, Changchun, China.

Cancer Med ; 12(5): 5939-5952, 2023 03.

Article em En | MEDLINE | ID: mdl-36373232

Assuntos

Células Supressoras Mieloides; Neoplasias de Mama Triplo Negativas; Animais; Camundongos; DNA/farmacologia; Gencitabina; Leucócitos Mononucleares; Neoplasias de Mama Triplo Negativas/tratamento farmacológico; Neoplasias de Mama Triplo Negativas/genética

Palavras-chave

DNA-PK; MDSCs; NU7441; TNBC; immunosuppressive function; tumor progression

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias de Mama Triplo Negativas / Células Supressoras Mieloides Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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