Evaluation of the 5-HT<sub>2C</sub> receptor drugs RO 60-0175, WAY 161503 and mirtazepine in a preclinical model of comorbidity of depression and cocaine addiction.

Jastrzebska, Joanna; Frankowska, Malgorzata; Smaga, Irena; Hubalewska-Mazgaj, Magdalena; Suder, Agata; Pieniazek, Renata; Przegalinski, Edmund; Filip, Malgorzata

Evaluation of the 5-HT_2C receptor drugs RO 60-0175, WAY 161503 and mirtazepine in a preclinical model of comorbidity of depression and cocaine addiction.

Jastrzebska, Joanna; Frankowska, Malgorzata; Smaga, Irena; Hubalewska-Mazgaj, Magdalena; Suder, Agata; Pieniazek, Renata; Przegalinski, Edmund; Filip, Malgorzata.

Afiliação

Jastrzebska J; Maj Institute of Pharmacology, Department of Drug Addiction Pharmacology, Polish Academy of Sciences, Smetna 12, 31-343, Kraków, Poland.
Frankowska M; Maj Institute of Pharmacology, Department of Drug Addiction Pharmacology, Polish Academy of Sciences, Smetna 12, 31-343, Kraków, Poland. frankow@if-pan.krakow.pl.
Smaga I; Maj Institute of Pharmacology, Department of Drug Addiction Pharmacology, Polish Academy of Sciences, Smetna 12, 31-343, Kraków, Poland.
Hubalewska-Mazgaj M; Maj Institute of Pharmacology, Department of Drug Addiction Pharmacology, Polish Academy of Sciences, Smetna 12, 31-343, Kraków, Poland.
Suder A; Maj Institute of Pharmacology, Department of Drug Addiction Pharmacology, Polish Academy of Sciences, Smetna 12, 31-343, Kraków, Poland.
Pieniazek R; Maj Institute of Pharmacology, Department of Drug Addiction Pharmacology, Polish Academy of Sciences, Smetna 12, 31-343, Kraków, Poland.
Przegalinski E; Maj Institute of Pharmacology, Department of Drug Addiction Pharmacology, Polish Academy of Sciences, Smetna 12, 31-343, Kraków, Poland.
Filip M; Maj Institute of Pharmacology, Department of Drug Addiction Pharmacology, Polish Academy of Sciences, Smetna 12, 31-343, Kraków, Poland.

Pharmacol Rep ; 75(1): 99-118, 2023 Feb.

Article em En | MEDLINE | ID: mdl-36374478

Assuntos

Transtornos Relacionados ao Uso de Cocaína; Cocaína; Ratos; Masculino; Animais; Transtornos Relacionados ao Uso de Cocaína/tratamento farmacológico; Serotonina/farmacologia; Preparações Farmacêuticas; Receptor 5-HT2C de Serotonina; Depressão/tratamento farmacológico; Extinção Psicológica; Comorbidade; Autoadministração

Palavras-chave

5-HT2C receptor; Addiction; Bulbectomy; Cocaine self-administration; Depression; Rats

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cocaína / Transtornos Relacionados ao Uso de Cocaína Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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