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Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice.
Wang, Xuanchun; Li, Yanliang; Qiang, Guifen; Wang, Kaihua; Dai, Jiarong; McCann, Maximilian; Munoz, Marcos D; Gil, Victoria; Yu, Yifei; Li, Shengxian; Yang, Zhihong; Xu, Shanshan; Cordoba-Chacon, Jose; De Jesus, Dario F; Sun, Bei; Chen, Kuangyang; Wang, Yahao; Liu, Xiaoxia; Miao, Qing; Zhou, Linuo; Hu, Renming; Ding, Qiang; Kulkarni, Rohit N; Gao, Daming; Blüher, Matthias; Liew, Chong Wee.
Afiliação
  • Wang X; Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China. wangxch@fudan.edu.cn.
  • Li Y; Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China.
  • Qiang G; Department of Physiology & Biophysics, University of Illinois at Chicago, Chicago, IL, USA.
  • Wang K; Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, USA.
  • Dai J; Department of Physiology & Biophysics, University of Illinois at Chicago, Chicago, IL, USA.
  • McCann M; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Munoz MD; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, CAS Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.
  • Gil V; University of Chinese Academy of Sciences, Beijing, China.
  • Yu Y; Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China.
  • Li S; Department of Physiology & Biophysics, University of Illinois at Chicago, Chicago, IL, USA.
  • Yang Z; Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, USA.
  • Xu S; Department of Physiology & Biophysics, University of Illinois at Chicago, Chicago, IL, USA.
  • Cordoba-Chacon J; Department of Physiology & Biophysics, University of Illinois at Chicago, Chicago, IL, USA.
  • De Jesus DF; Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China.
  • Sun B; Department of Physiology & Biophysics, University of Illinois at Chicago, Chicago, IL, USA.
  • Chen K; Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  • Wang Y; Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
  • Liu X; Department of Transplant Surgery, Mass General Hospital, Harvard Medical School, Boston, MA, USA.
  • Miao Q; Department of Physiology & Biophysics, University of Illinois at Chicago, Chicago, IL, USA.
  • Zhou L; Department of Medicine, Section of Endocrinology, Diabetes and Metabolism, University of Illinois at Chicago, Chicago, IL, USA.
  • Hu R; Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
  • Ding Q; NHC Key Laboratory of Hormones and Development, Tianjin Key Laboratory of Metabolic Diseases, Chu Hsien-I Memorial Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, China.
  • Kulkarni RN; Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China.
  • Gao D; Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China.
  • Blüher M; Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China.
  • Liew CW; Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China.
Nat Commun ; 13(1): 7323, 2022 11 28.
Article em En | MEDLINE | ID: mdl-36443308
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Anticorpos Neutralizantes Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Anticorpos Neutralizantes Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article