Precise modulation of embryonic development through optogenetics.
Genesis
; 60(10-12): e23505, 2022 12.
Article
em En
| MEDLINE
| ID: mdl-36478118
ABSTRACT
The past decade has witnessed enormous progress in optogenetics, which uses photo-sensitive proteins to control signal transduction in live cells and animals. The ever-increasing amount of optogenetic tools, however, could overwhelm the selection of appropriate optogenetic strategies. In this work, we summarize recent progress in this emerging field and highlight the application of opsin-free optogenetics in studying embryonic development, focusing on new insights gained into optical induction of morphogenesis, cell polarity, cell fate determination, tissue differentiation, neuronal regeneration, synaptic plasticity, and removal of cells during development.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transdução de Sinais
/
Optogenética
Limite:
Animals
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article