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Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone-A Pilot Case Study.
Findrik Balogová, Alena; Kozár, Martin; Staronová, Radka; Schnitzer, Marek; Dancáková, Gabriela; Zivcák, Jozef; Hudák, Radovan.
Afiliação
  • Findrik Balogová A; Department of Biomedical Engineering and Measurement, Faculty of Mechanical Engineering, Technical University of Kosice, 042 00 Kosice, Slovakia.
  • Kozár M; Small Animal Clinic, University Veterinary Hospital, University of Veterinary Medicine and Pharmacy in Kosice, Komenského 73, 041 81 Kosice, Slovakia.
  • Staronová R; Small Animal Clinic, University Veterinary Hospital, University of Veterinary Medicine and Pharmacy in Kosice, Komenského 73, 041 81 Kosice, Slovakia.
  • Schnitzer M; Department of Biomedical Engineering and Measurement, Faculty of Mechanical Engineering, Technical University of Kosice, 042 00 Kosice, Slovakia.
  • Dancáková G; Department of Biomedical Engineering and Measurement, Faculty of Mechanical Engineering, Technical University of Kosice, 042 00 Kosice, Slovakia.
  • Zivcák J; Department of Biomedical Engineering and Measurement, Faculty of Mechanical Engineering, Technical University of Kosice, 042 00 Kosice, Slovakia.
  • Hudák R; Department of Biomedical Engineering and Measurement, Faculty of Mechanical Engineering, Technical University of Kosice, 042 00 Kosice, Slovakia.
Polymers (Basel) ; 14(23)2022 Dec 03.
Article em En | MEDLINE | ID: mdl-36501687
ABSTRACT
This case study describes the use of additive manufacturing technology combining a biodegradable polymer material, polycaprolactone (PCL), and innovative procedures for creating superficial wound dressing, a scaffold in the therapy of extensive contaminated skin defects caused by a traumatic injury. Chronic and contaminated wounds represent a clinical problem and require intensive wound care. The application of a temporary scaffold-facilitated bridging of the wound edges resulted in faster tissue regeneration and a shorter defect closure time, compared to other conservative and surgical methods used in therapy of chronic wounds. Although this procedure has proven to be an optimal alternative to autologous transplants, further studies with a larger number of patients would be beneficial.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article