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Pharmacologic Inhibition of SHP2 Blocks Both PI3K and MEK Signaling in Low-epiregulin HNSCC via GAB1.
Kurupi, Richard; Floros, Konstantinos V; Jacob, Sheeba; Chawla, Ayesha T; Cai, Jinyang; Hu, Bin; Puchalapalli, Madhavi; Coon, Colin M; Khatri, Rishabh; Crowther, Giovanna Stein; Egan, Regina K; Murchie, Ellen; Greninger, Patricia; Dalton, Krista M; Ghotra, Maninderjit S; Boikos, Sosipatros A; Koblinski, Jennifer E; Harada, Hisashi; Sun, Yue; Morgan, Iain M; Basu, Devraj; Dozmorov, Mikhail G; Benes, Cyril H; Faber, Anthony C.
Afiliação
  • Kurupi R; VCU Philips Institute, School of Dentistry and Massey Cancer Center; Richmond, Virginia 23298.
  • Floros KV; VCU Philips Institute, School of Dentistry and Massey Cancer Center; Richmond, Virginia 23298.
  • Jacob S; VCU Philips Institute, School of Dentistry and Massey Cancer Center; Richmond, Virginia 23298.
  • Chawla AT; VCU Philips Institute, School of Dentistry and Massey Cancer Center; Richmond, Virginia 23298.
  • Cai J; VCU Philips Institute, School of Dentistry and Massey Cancer Center; Richmond, Virginia 23298.
  • Hu B; Department of Pathology, Virginia Commonwealth University School of Medicine, Richmond, VA 23220.
  • Puchalapalli M; Department of Pathology, Virginia Commonwealth University School of Medicine, Richmond, VA 23220.
  • Coon CM; VCU Philips Institute, School of Dentistry and Massey Cancer Center; Richmond, Virginia 23298.
  • Khatri R; VCU Philips Institute, School of Dentistry and Massey Cancer Center; Richmond, Virginia 23298.
  • Crowther GS; Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.
  • Egan RK; Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.
  • Murchie E; Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.
  • Greninger P; Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.
  • Dalton KM; VCU Philips Institute, School of Dentistry and Massey Cancer Center; Richmond, Virginia 23298.
  • Ghotra MS; VCU Philips Institute, School of Dentistry and Massey Cancer Center; Richmond, Virginia 23298.
  • Boikos SA; Georgetown Lombardi Comprehensive Cancer Center, Washington, DC, 20057.
  • Koblinski JE; Department of Pathology, Virginia Commonwealth University School of Medicine, Richmond, VA 23220.
  • Harada H; VCU Philips Institute, School of Dentistry and Massey Cancer Center; Richmond, Virginia 23298.
  • Sun Y; VCU Philips Institute, School of Dentistry and Massey Cancer Center; Richmond, Virginia 23298.
  • Morgan IM; VCU Philips Institute, School of Dentistry and Massey Cancer Center; Richmond, Virginia 23298.
  • Basu D; Department of Otorhinolaryngology-Head and Neck Surgery, The University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.
  • Dozmorov MG; Department of Biostatistics, Virginia Commonwealth University School of Medicine, Richmond, VA 23220.
  • Benes CH; Department of Pathology, Virginia Commonwealth University, Richmond, VA, USA.
  • Faber AC; Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.
Cancer Res Commun ; 2(9): 1061-1074, 2022 09.
Article em En | MEDLINE | ID: mdl-36506869
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfatidilinositol 3-Quinases / Neoplasias de Cabeça e Pescoço Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfatidilinositol 3-Quinases / Neoplasias de Cabeça e Pescoço Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article