Indole-derived compound SIS3 targets a subset of activated Smad complexes.

Itoh, Yuka; Sawaguchi, Tomoe; Fu, Hao; Omata, Chiho; Saitoh, Masao; Miyazawa, Keiji

Itoh, Yuka; Sawaguchi, Tomoe; Fu, Hao; Omata, Chiho; Saitoh, Masao; Miyazawa, Keiji.

Afiliação

Itoh Y; Department of Biochemistry, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Sawaguchi T; Department of Biochemistry, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Fu H; Research Training Program for Undergraduates, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Omata C; Department of Biochemistry, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Saitoh M; Department of Biochemistry, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.
Miyazawa K; Department of Biochemistry, University of Yamanashi, Shimokato 1110, Chuo, Yamanashi 409-3898, Japan.

J Biochem ; 173(4): 283-291, 2023 Mar 31.

Article em En | MEDLINE | ID: mdl-36539324

Assuntos

Proteínas Smad; Fator de Crescimento Transformador beta; Fator de Crescimento Transformador beta/metabolismo; Proteínas Smad/metabolismo; Linhagem Celular; Transdução de Sinais; Fosforilação; Proteína Smad3/genética; Proteína Smad2/genética; Proteína Smad2/metabolismo

Palavras-chave

SIS3; Smad3; TGF-ß; pharmacological inhibitor; transcription

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Proteínas Smad Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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