Overexpression of SMS in the tumor microenvironment is associated with immunosuppression in hepatocellular carcinoma.

Xiang, Lin; Piao, Longhuan; Wang, Dong; Qi, Li-Feng-Rong

Xiang, Lin; Piao, Longhuan; Wang, Dong; Qi, Li-Feng-Rong.

Afiliação

Xiang L; Department of Translational Medicine Research Institute, Jiangsu Yifengrong Biotechnology Co., Ltd., Nanjing, Jiangsu, China.
Piao L; Department of Orthopedic Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Wang D; Department of Histology and Embryology, Binzhou Medical University, Yantai, Shandong, China.
Qi LF; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, China.

Front Immunol ; 13: 974241, 2022.

Article em En | MEDLINE | ID: mdl-36544774

Assuntos

Carcinoma Hepatocelular; Neoplasias Hepáticas; Humanos; Carcinoma Hepatocelular/genética; Espermina Sintase; Microambiente Tumoral; Neoplasias Hepáticas/genética; Terapia de Imunossupressão; Poliaminas

Palavras-chave

hepatocellular carcinoma; immune checkpoint blockade (ICB); polyamine metabolism; spermine synthase; tumor immune microenvironment (TIME)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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