GATA3 Encapsulated by Tumor-Associated Macrophage-Derived Extracellular Vesicles Promotes Immune Escape and Chemotherapy Resistance of Ovarian Cancer Cells by Upregulating the CD24/Siglec-10 Axis.

Chen, Chao; Zhang, Li; Ruan, Zhengyi

Chen, Chao; Zhang, Li; Ruan, Zhengyi.

Afiliação

Chen C; Department of Obstetrics and Gynecology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200011, P.R. China.
Zhang L; Department of Obstetrics and Gynecology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200011, P.R. China.
Ruan Z; Department of Obstetrics and Gynecology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200011, P.R. China.

Mol Pharm ; 20(2): 971-986, 2023 02 06.

Article em En | MEDLINE | ID: mdl-36547230

Assuntos

Vesículas Extracelulares; Neoplasias Ovarianas; Humanos; Feminino; Macrófagos Associados a Tumor/metabolismo; Neoplasias Ovarianas/tratamento farmacológico; Neoplasias Ovarianas/metabolismo; Vesículas Extracelulares/metabolismo; Linhagem Celular Tumoral; Lectinas Semelhantes a Imunoglobulina de Ligação ao Ácido Siálico/metabolismo; Fator de Transcrição GATA3/metabolismo; Antígeno CD24/genética; Antígeno CD24/metabolismo

Palavras-chave

CD24; GATA-binding protein-3; extracellular vesicles; ovarian cancer; sialic acid-binding igg-like lectin 10; tumor-associated macrophage

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Vesículas Extracelulares Tipo de estudo: Risk_factors_studies Limite: Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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