N-Acetylcysteine Administration Attenuates Sensorimotor Impairments Following Neonatal Hypoxic-Ischemic Brain Injury in Rats.

Kesidou, Evangelia; Bitsina, Christina; Chatzisotiriou, Athanasios; Theotokis, Paschalis; Dandi, Evgenia; Tata, Despina A; Spandou, Evangelia

Kesidou, Evangelia; Bitsina, Christina; Chatzisotiriou, Athanasios; Theotokis, Paschalis; Dandi, Evgenia; Tata, Despina A; Spandou, Evangelia.

Afiliação

Kesidou E; Laboratory of Experimental Neurology and Neuroimmunology, 2nd Department of Neurology, AHEPA University Hospital, Aristotle University of Thessaloniki, 546 36 Thessaloniki, Greece.
Bitsina C; Laboratory of Physiology, Faculty of Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Chatzisotiriou A; Laboratory of Experimental Neurology and Neuroimmunology, 2nd Department of Neurology, AHEPA University Hospital, Aristotle University of Thessaloniki, 546 36 Thessaloniki, Greece.
Theotokis P; Laboratory of Physiology, Faculty of Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Dandi E; Laboratory of Physiology, Faculty of Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Tata DA; Laboratory of Experimental Neurology and Neuroimmunology, 2nd Department of Neurology, AHEPA University Hospital, Aristotle University of Thessaloniki, 546 36 Thessaloniki, Greece.
Spandou E; Laboratory of Cognitive Neuroscience, School of Psychology, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.

Int J Mol Sci ; 23(24)2022 Dec 19.

Article em En | MEDLINE | ID: mdl-36555816

Assuntos

Lesões Encefálicas; Hipóxia-Isquemia Encefálica; Fármacos Neuroprotetores; Animais; Ratos; Acetilcisteína/farmacologia; Acetilcisteína/uso terapêutico; Acetilcisteína/metabolismo; Animais Recém-Nascidos; Ratos Sprague-Dawley; Hipóxia-Isquemia Encefálica/metabolismo; Lesões Encefálicas/metabolismo; Fármacos Neuroprotetores/farmacologia; Fármacos Neuroprotetores/uso terapêutico; Fármacos Neuroprotetores/metabolismo; Encéfalo/metabolismo

Palavras-chave

N-acetylcysteine (NAC); brain injury; hypoxia; inducible nitric oxide synthase (iNOS); ischemia; neuroprotection; sensorimotor tests

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lesões Encefálicas / Fármacos Neuroprotetores / Hipóxia-Isquemia Encefálica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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