<i>Isocitrate Dehydrogenase Alpha-1</i> Modulates Lifespan and Oxidative Stress Tolerance in <i>Caenorhabditis elegans</i>.

Lin, Zhi-Han; Chang, Shun-Ya; Shen, Wen-Chi; Lin, Yen-Hung; Shen, Chiu-Lun; Liao, Sin-Bo; Liu, Yu-Chun; Chen, Chang-Shi; Ching, Tsui-Ting; Wang, Horng-Dar

Isocitrate Dehydrogenase Alpha-1 Modulates Lifespan and Oxidative Stress Tolerance in Caenorhabditis elegans.

Lin, Zhi-Han; Chang, Shun-Ya; Shen, Wen-Chi; Lin, Yen-Hung; Shen, Chiu-Lun; Liao, Sin-Bo; Liu, Yu-Chun; Chen, Chang-Shi; Ching, Tsui-Ting; Wang, Horng-Dar.

Afiliação

Lin ZH; Institute of Biotechnology, National Tsing Hua University, Hsinchu 300044, Taiwan.
Chang SY; Institute of Chemistry, Academia Sinica, Taipei 115201, Taiwan.
Shen WC; Chemical Biology and Molecular Biophysics Program, Taiwan International Graduate Program, Academia Sinica, Taipei 115201, Taiwan.
Lin YH; Institute of Biochemical Sciences, National Taiwan University, Taipei 106319, Taiwan.
Shen CL; Institute of Biotechnology, National Tsing Hua University, Hsinchu 300044, Taiwan.
Liao SB; Institute of Biotechnology, National Tsing Hua University, Hsinchu 300044, Taiwan.
Liu YC; Institute of Biotechnology, National Tsing Hua University, Hsinchu 300044, Taiwan.
Chen CS; Department of Life Science, National Tsing Hua University, Hsinchu 300044, Taiwan.
Ching TT; Institute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan.
Wang HD; Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei 10002, Taiwan.

Int J Mol Sci ; 24(1)2022 Dec 29.

Article em En | MEDLINE | ID: mdl-36614054

Assuntos

Proteínas de Caenorhabditis elegans; Caenorhabditis elegans; Isocitrato Desidrogenase; Longevidade; Estresse Oxidativo; Animais; Caenorhabditis elegans/enzimologia; Caenorhabditis elegans/genética; Proteínas de Caenorhabditis elegans/genética; Proteínas de Caenorhabditis elegans/metabolismo; Isocitrato Desidrogenase/genética; Isocitrato Desidrogenase/metabolismo; Longevidade/genética

Palavras-chave

C. elegans; TCA cycle; TOR pathway; dietary restriction; idha-1; longevity; oxidative stress

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Caenorhabditis elegans / Estresse Oxidativo / Proteínas de Caenorhabditis elegans / Isocitrato Desidrogenase / Longevidade Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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