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Treatment of chronic relapsing urinary tract infection with antibiotics selected by AtbFinder.
Tetz, George V; Kardava, Kristina M; Vecherkovskaya, Maria F; Tsifansky, Michael D; Tetz, Victor V.
Afiliação
  • Tetz GV; Human Microbiology Institute, New York, NY, USA.
  • Kardava KM; Human Microbiology Institute, New York, NY, USA.
  • Vecherkovskaya MF; Human Microbiology Institute, New York, NY, USA.
  • Tsifansky MD; Department of Pediatrics, George Washington University (GWU), Washington, DC, USA.
  • Tetz VV; Divisions of Cardiac Critical Care Medicine and Pulmonary, Children's National Hospital, Washington, DC, USA.
Urol Case Rep ; 46: 102312, 2023 Jan.
Article em En | MEDLINE | ID: mdl-36619660
We report the case of a 46-year-old patient who, after renal cancer surgery, developed a recurrent urinary tract infection that lasted for more than 2 years. Despite repeated antibiotic courses, including broad-spectrum drugs chosen using conventional antibiotic susceptibility testing, multiple reinfections followed. The patient was successfully treated once antibiotics were selected with AtbFinder. Unlike routine antimicrobial susceptibility methods, which select antibiotics effective only against a "lead bacterial pathogen," AtbFinder identifies antibiotics that target the mixture of bacteria at the infection site. This case demonstrates the ability of AtbFinder to successfully select antibiotics for the treatment of relapsing urinary tract infections.
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article