Opioid-Modulated Receptor Localization and Erk1/2 Phosphorylation in Cells Coexpressing µ-Opioid and Nociceptin Receptors.

Zhuo, Guan-Yu; Chen, Ming-Chi; Lin, Tzu-Yu; Lin, Shih-Ting; Chen, Daniel Tzu-Li; Lee, Cynthia Wei-Sheng

Zhuo, Guan-Yu; Chen, Ming-Chi; Lin, Tzu-Yu; Lin, Shih-Ting; Chen, Daniel Tzu-Li; Lee, Cynthia Wei-Sheng.

Afiliação

Zhuo GY; Institute of Translational Medicine and New Drug Development, China Medical University, Taichung 40402, Taiwan.
Chen MC; Institute of Translational Medicine and New Drug Development, China Medical University, Taichung 40402, Taiwan.
Lin TY; Center for Drug Abuse and Addiction, China Medical University Hospital, Taichung 40447, Taiwan.
Lin ST; Integrative Stem Cell Center, China Medical University Hospital, Taichung 40447, Taiwan.
Chen DT; School of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.
Lee CW; Graduate Institute of Biomedical Sciences, China Medical University, Taichung 40402, Taiwan.

Int J Mol Sci ; 24(2)2023 Jan 05.

Article em En | MEDLINE | ID: mdl-36674576

Assuntos

Buprenorfina; Receptores Opioides; Humanos; Receptores Opioides/metabolismo; Receptor de Nociceptina; Analgésicos Opioides/farmacologia; Células HEK293; Fosforilação; Receptores Opioides mu/metabolismo; Buprenorfina/farmacologia; Morfina/farmacologia

Palavras-chave

Erk1/2 (p44/p42 MAPK); fluorescence resonance energy transfer (FRET); lipid rafts; nociceptin/orphanin FQ (NOP) receptor; single-particle tracking (SPT); two-photon microscopy; µ-opioid (MOP) receptor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Buprenorfina / Receptores Opioides Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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