Boris knockout eliminates AOM/DSS-induced in situ colorectal cancer by suppressing DNA damage repair and inflammation.

Zuo, Bo-Wen; Yao, Wan-Xin; Fang, Meng-Die; Ren, Juan; Tu, Ling-Lan; Fan, Run-Jie; Zhang, Yan-Mei

Zuo, Bo-Wen; Yao, Wan-Xin; Fang, Meng-Die; Ren, Juan; Tu, Ling-Lan; Fan, Run-Jie; Zhang, Yan-Mei.

Afiliação

Zuo BW; School of Laboratory Medicine and Bioengineering, Hangzhou Medical College, Hangzhou, China.
Yao WX; School of Laboratory Medicine and Bioengineering, Hangzhou Medical College, Hangzhou, China.
Fang MD; School of Laboratory Medicine and Bioengineering, Hangzhou Medical College, Hangzhou, China.
Ren J; School of Laboratory Medicine and Bioengineering, Hangzhou Medical College, Hangzhou, China.
Tu LL; School of Laboratory Medicine and Bioengineering, Hangzhou Medical College, Hangzhou, China.
Fan RJ; School of Laboratory Medicine and Bioengineering, Hangzhou Medical College, Hangzhou, China.
Zhang YM; School of Laboratory Medicine and Bioengineering, Hangzhou Medical College, Hangzhou, China.

Cancer Sci ; 114(5): 1972-1985, 2023 May.

Article em En | MEDLINE | ID: mdl-36692143

Assuntos

Colite; Neoplasias Colorretais; Animais; Masculino; Camundongos; Azoximetano/toxicidade; Colite/induzido quimicamente; Colite/genética; Colite/complicações; Neoplasias Colorretais/induzido quimicamente; Neoplasias Colorretais/genética; Neoplasias Colorretais/tratamento farmacológico; Sulfato de Dextrana/toxicidade; Sulfato de Dextrana/uso terapêutico; Modelos Animais de Doenças; Dano ao DNA/genética; Inflamação/metabolismo; Camundongos Endogâmicos C57BL; Camundongos Knockout

Palavras-chave

Boris; DNA damage repair; colitis; colorectal cancer; inflammation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Colite Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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