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Oral arsenic administration to humanizedUDP-glucuronosyltransferase1 neonatal mice induces UGT1A1 through a dependence on Nrf2 and PXR.
Yang, Xiaojing; Weber, André A; Mennillo, Elvira; Paszek, Miles; Wong, Samantha; Le, Sabrina; Teo, Jia Ying Ashley; Chang, Max; Benner, Christopher W; Tukey, Robert H; Chen, Shujuan.
Afiliação
  • Yang X; Laboratory of Environmental Toxicology, Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, California, USA.
  • Weber AA; Laboratory of Environmental Toxicology, Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, California, USA.
  • Mennillo E; Laboratory of Environmental Toxicology, Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, California, USA.
  • Paszek M; Laboratory of Environmental Toxicology, Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, California, USA.
  • Wong S; Laboratory of Environmental Toxicology, Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, California, USA.
  • Le S; Laboratory of Environmental Toxicology, Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, California, USA.
  • Teo JYA; Laboratory of Environmental Toxicology, Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, California, USA.
  • Chang M; Department of Medicine, School of Medicine, University of California San Diego, La Jolla, California, USA.
  • Benner CW; Department of Medicine, School of Medicine, University of California San Diego, La Jolla, California, USA.
  • Tukey RH; Laboratory of Environmental Toxicology, Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, California, USA.
  • Chen S; Laboratory of Environmental Toxicology, Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, California, USA. Electronic address: s18chen@health.ucsd.edu.
J Biol Chem ; 299(3): 102955, 2023 03.
Article em En | MEDLINE | ID: mdl-36720308
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arsênio / Glucuronosiltransferase / Fator 2 Relacionado a NF-E2 / Receptor de Pregnano X Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arsênio / Glucuronosiltransferase / Fator 2 Relacionado a NF-E2 / Receptor de Pregnano X Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article