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Pyrido-Dibemequine Metabolites Exhibit Improved Druglike Features, Inhibit Hemozoin Formation in Plasmodium falciparum, and Synergize with Clinical Antimalarials.
Okombo, John; Kumar, Malkeet; Redhi, Devasha; Wicht, Kathryn J; Wiesner, Lubbe; Egan, Timothy J; Chibale, Kelly.
Afiliação
  • Okombo J; Department of Chemistry, University of Cape Town, Rondebosch, 7701 Cape Town, South Africa.
  • Kumar M; Department of Chemistry, University of Cape Town, Rondebosch, 7701 Cape Town, South Africa.
  • Redhi D; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Observatory, 7925 Cape Town, South Africa.
  • Wicht KJ; Department of Chemistry, University of Cape Town, Rondebosch, 7701 Cape Town, South Africa.
  • Wiesner L; South African Medical Research Council Drug Discovery and Development Research Unit, Holistic Drug Discovery and Development (H3D) Centre, Rondebosch, 7701 Cape Town, South Africa.
  • Egan TJ; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch, 7701 Cape Town, South Africa.
  • Chibale K; Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Observatory, 7925 Cape Town, South Africa.
ACS Infect Dis ; 9(3): 653-667, 2023 03 10.
Article em En | MEDLINE | ID: mdl-36802523
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antimaláricos Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antimaláricos Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article