Therapeutic targeting of vascular malformation in a zebrafish model of hereditary haemorrhagic telangiectasia.

Snodgrass, Ryan O; Govindpani, Karan; Plant, Karen; Kugler, Elisabeth C; Doh, Changmin; Dawson, Thomas; McCormack, Luis E; Arthur, Helen M; Chico, Timothy J A

Snodgrass, Ryan O; Govindpani, Karan; Plant, Karen; Kugler, Elisabeth C; Doh, Changmin; Dawson, Thomas; McCormack, Luis E; Arthur, Helen M; Chico, Timothy J A.

Afiliação

Snodgrass RO; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.
Govindpani K; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.
Plant K; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.
Kugler EC; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.
Doh C; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.
Dawson T; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.
McCormack LE; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.
Arthur HM; Biosciences Institute, Centre for Life, Newcastle University, Newcastle NE1 3BZ, UK.
Chico TJA; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK.

Dis Model Mech ; 16(4)2023 04 01.

Article em En | MEDLINE | ID: mdl-36861761

Assuntos

Malformações Arteriovenosas; Telangiectasia Hemorrágica Hereditária; Animais; Telangiectasia Hemorrágica Hereditária/tratamento farmacológico; Telangiectasia Hemorrágica Hereditária/genética; Peixe-Zebra/metabolismo; Endoglina/genética; Fator A de Crescimento do Endotélio Vascular/genética; Malformações Arteriovenosas/genética; Serina-Treonina Quinases TOR; Quinases de Proteína Quinase Ativadas por Mitógeno/genética; Receptores de Activinas Tipo II/genética; Mutação/genética

Palavras-chave

Angiogenesis; Endoglin; HHT; VEGF; Zebrafish

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Malformações Arteriovenosas / Telangiectasia Hemorrágica Hereditária Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google