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Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy.
Cohen Saban, Noy; Yalin, Adam; Landsberger, Tomer; Salomon, Ran; Alva, Ajjai; Feferman, Tali; Amit, Ido; Dahan, Rony.
Afiliação
  • Cohen Saban N; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.
  • Yalin A; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.
  • Landsberger T; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.
  • Salomon R; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.
  • Alva A; University of Michigan Cancer Center, Ann Arbor, MI, USA.
  • Feferman T; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.
  • Amit I; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.
  • Dahan R; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.
Sci Immunol ; 8(81): eadd8005, 2023 03 10.
Article em En | MEDLINE | ID: mdl-36867679

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de IgG / Anticorpos Monoclonais Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de IgG / Anticorpos Monoclonais Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article