An extracellular matrix stiffness-induced breast cancer cell transcriptome resembles the transition from ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC).

Göransson, Sara; Chen, Shan; Olofsson, Helene; Larsson, Ola; Strömblad, Staffan

Göransson, Sara; Chen, Shan; Olofsson, Helene; Larsson, Ola; Strömblad, Staffan.

Afiliação

Göransson S; Department of Biosciences and Nutrition, Karolinska Institutet, SE-141 83, Huddinge, Sweden.
Chen S; Department of Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, SE-171 65, Solna, Sweden.
Olofsson H; Department of Biosciences and Nutrition, Karolinska Institutet, SE-141 83, Huddinge, Sweden.
Larsson O; Department of Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, SE-171 65, Solna, Sweden. Electronic address: ola.larsson@ki.se.
Strömblad S; Department of Biosciences and Nutrition, Karolinska Institutet, SE-141 83, Huddinge, Sweden. Electronic address: staffan.stromblad@ki.se.

Biochem Biophys Res Commun ; 654: 73-79, 2023 04 30.

Article em En | MEDLINE | ID: mdl-36893606

Assuntos

Neoplasias da Mama; Carcinoma in Situ; Carcinoma Ductal de Mama; Carcinoma Intraductal não Infiltrante; Humanos; Feminino; Carcinoma Intraductal não Infiltrante/genética; Carcinoma Intraductal não Infiltrante/patologia; Carcinoma Ductal de Mama/genética; Carcinoma Ductal de Mama/patologia; Transcriptoma; Matriz Extracelular/genética; Matriz Extracelular/patologia; Neoplasias da Mama/genética; Neoplasias da Mama/patologia

Palavras-chave

Breast cancer; DCIS; Matrix stiffness; Mechanotransduction; Transcriptomics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Carcinoma in Situ / Carcinoma Ductal de Mama / Carcinoma Intraductal não Infiltrante Limite: Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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