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Pharmacokinetic evaluation of poorly soluble compounds formulated as nano- or microcrystals after intraperitoneal injection to mice.
Aluri, Krishna C; Sigfridsson, Kalle; Xue, Aixiang; Hariparsad, Niresh; McGinnity, Dermot; Ramsden, Diane.
Afiliação
  • Aluri KC; Drug Metabolism and Pharmacokinetics, Oncology R&D, AstraZeneca, Boston, USA. Electronic address: krishnachaitanya.aluri@astrazeneca.com.
  • Sigfridsson K; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Gothenburg, Sweden.
  • Xue A; Animal Sciences and Technologies, Clinical Pharmacology and Safety Sciences, AstraZeneca, Boston, USA.
  • Hariparsad N; Drug Metabolism and Pharmacokinetics, Oncology R&D, AstraZeneca, Boston, USA.
  • McGinnity D; Drug Metabolism and Pharmacokinetics, Oncology R&D, AstraZeneca, Cambridge, UK.
  • Ramsden D; Drug Metabolism and Pharmacokinetics, Oncology R&D, AstraZeneca, Boston, USA.
Int J Pharm ; 636: 122787, 2023 Apr 05.
Article em En | MEDLINE | ID: mdl-36894042
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanopartículas Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanopartículas Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article