Liraglutide Lowers Endothelial Vascular Cell Adhesion Molecule-1 in Murine Atherosclerosis Independent of Glucose Levels.

Punjabi, Mukesh; Kosareva, Alexandra; Xu, Lifen; Ochoa-Espinosa, Amanda; Decembrini, Sarah; Hofmann, Georg; Wyttenbach, Samira; Rolin, Bidda; Nyberg, Michael; Kaufmann, Beat A

Liraglutide Lowers Endothelial Vascular Cell Adhesion Molecule-1 in Murine Atherosclerosis Independent of Glucose Levels.

Punjabi, Mukesh; Kosareva, Alexandra; Xu, Lifen; Ochoa-Espinosa, Amanda; Decembrini, Sarah; Hofmann, Georg; Wyttenbach, Samira; Rolin, Bidda; Nyberg, Michael; Kaufmann, Beat A.

Afiliação

Punjabi M; Cardiovascular Molecular Imaging, Department of Biomedicine, University of Basel, Basel, Switzerland.
Kosareva A; Cardiovascular Molecular Imaging, Department of Biomedicine, University of Basel, Basel, Switzerland.
Xu L; Cardiovascular Molecular Imaging, Department of Biomedicine, University of Basel, Basel, Switzerland.
Ochoa-Espinosa A; Cardiovascular Molecular Imaging, Department of Biomedicine, University of Basel, Basel, Switzerland.
Decembrini S; Cardiovascular Molecular Imaging, Department of Biomedicine, University of Basel, Basel, Switzerland.
Hofmann G; Cardiovascular Molecular Imaging, Department of Biomedicine, University of Basel, Basel, Switzerland.
Wyttenbach S; Cardiovascular Molecular Imaging, Department of Biomedicine, University of Basel, Basel, Switzerland.
Rolin B; Global Drug Discovery, Novo Nordisk A/S, Maaloev, Denmark.
Nyberg M; Global Drug Discovery, Novo Nordisk A/S, Maaloev, Denmark.
Kaufmann BA; Cardiovascular Molecular Imaging, Department of Biomedicine, University of Basel, Basel, Switzerland.

JACC Basic Transl Sci ; 8(2): 189-200, 2023 Feb.

Article em En | MEDLINE | ID: mdl-36908664

Palavras-chave

ApoE, apolipoprotein E; CEUMI, contrast-enhanced ultrasound molecular imaging; CVD, cardiovascular disease; GLP, glucagon-like peptide; GLP-1R, glucagon-like peptide-1 receptor; GLP-1RA, glucagon-like peptide-1 receptor agonist; HDL-C, high-density lipoprotein cholesterol; HbA1c, glycated hemoglobin; ICAM, intercellular cell adhesion molecule; IL, interleukin; LDL-C, low-density lipoprotein cholesterol; MB, microbubble; MBCtr, control microbubbles; MBVCAM-1, microbubbles targeted to VCAM; MCP, monocyte chemoattractant protein; OPN, osteopontin; TG, triglycerides; TGRL, triglyceride-rich lipoproteins; TNF, tumor necrosis factor; VCAM, vascular cell adhesion molecule; VLDL-C, very low-density lipoprotein cholesterol; atherosclerosis; liraglutide; molecular imaging; ultrasound

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article