A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution.

Chen, Yen-Hsi; Tian, Weihua; Yasuda, Makiko; Ye, Zilu; Song, Ming; Mandel, Ulla; Kristensen, Claus; Povolo, Lorenzo; Marques, André R A; Caval, Tomislav; Heck, Albert J R; Sampaio, Julio Lopes; Johannes, Ludger; Tsukimura, Takahiro; Desnick, Robert; Vakhrushev, Sergey Y; Yang, Zhang; Clausen, Henrik

Chen, Yen-Hsi; Tian, Weihua; Yasuda, Makiko; Ye, Zilu; Song, Ming; Mandel, Ulla; Kristensen, Claus; Povolo, Lorenzo; Marques, André R A; Caval, Tomislav; Heck, Albert J R; Sampaio, Julio Lopes; Johannes, Ludger; Tsukimura, Takahiro; Desnick, Robert; Vakhrushev, Sergey Y; Yang, Zhang; Clausen, Henrik.

Afiliação

Chen YH; Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Tian W; GlycoDisplay ApS, Copenhagen, Denmark.
Yasuda M; Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Ye Z; Department of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Song M; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Mandel U; Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Kristensen C; Novo Nordisk Foundation Center for Protein Research, Proteomics Program, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Povolo L; Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Marques ARA; Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Caval T; GlycoDisplay ApS, Copenhagen, Denmark.
Heck AJR; Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Sampaio JL; Biochemisches Institut, CAU Kiel, Kiel, Germany.
Johannes L; Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Tsukimura T; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Science4Life, Utrecht University and Netherlands Proteomics Centre, Utrecht, Netherlands.
Desnick R; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Science4Life, Utrecht University and Netherlands Proteomics Centre, Utrecht, Netherlands.
Vakhrushev SY; Institut Curie, PSL Research University, Cellular and Chemical Biology, U1143 INSERM, UMR3666 CNRS, Paris, France.
Yang Z; Institut Curie, PSL Research University, Cellular and Chemical Biology, U1143 INSERM, UMR3666 CNRS, Paris, France.
Clausen H; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.