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Investigating the trans-membrane transport of HAIYPRH peptide-decorated nano-drugs.
Zhang, Xiaowan; Shan, Meirong; Li, Siying; Zhao, Jing; Pang, Xuelei; Yang, Guocheng; Shan, Yuping.
Afiliação
  • Zhang X; School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China. shanyp@ciac.ac.cn.
  • Shan M; School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China. shanyp@ciac.ac.cn.
  • Li S; School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China. shanyp@ciac.ac.cn.
  • Zhao J; School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China. shanyp@ciac.ac.cn.
  • Pang X; School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China. shanyp@ciac.ac.cn.
  • Yang G; School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China. shanyp@ciac.ac.cn.
  • Shan Y; School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology, Changchun 130012, China. shanyp@ciac.ac.cn.
Phys Chem Chem Phys ; 25(14): 9766-9771, 2023 Apr 05.
Article em En | MEDLINE | ID: mdl-36946095
ABSTRACT
Transferrin (Tf) has been effectively used to promote the cellular uptake of HAIYPRH (T7) peptide-conjugated nano-drugs. In this study, the enhancing effect of Tf on T7-decorated nano-drug transport was investigated using force tracing and nano-indentation techniques at a single-particle/cell level. Furthermore, the results were confirmed by ensemble fluorescence imaging.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Transferrina Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Transferrina Idioma: En Ano de publicação: 2023 Tipo de documento: Article