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Repurposing 1,2,4-oxadiazoles as SARS-CoV-2 PLpro inhibitors and investigation of their possible viral entry blockade potential.
Ayoup, Mohammed Salah; ElShafey, Mariam M; Abdel-Hamid, Hamida; Ghareeb, Doaa A; Abu-Serie, Marwa M; Heikal, Lamia A; Teleb, Mohamed.
Afiliação
  • Ayoup MS; Department of Chemistry, Faculty of Science, Alexandria University, Alexandria, 21321, Egypt. Electronic address: Mohamed.salah@alexu.edu.eg.
  • ElShafey MM; Department of Chemistry, Faculty of Science, Alexandria University, Alexandria, 21321, Egypt.
  • Abdel-Hamid H; Department of Chemistry, Faculty of Science, Alexandria University, Alexandria, 21321, Egypt.
  • Ghareeb DA; Bio­screening and preclinical trial lab, Biochemistry Department, Faculty of Science, Alexandria University, P.O. Box 21511, Alexandria, Egypt.
  • Abu-Serie MM; Medical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Egypt.
  • Heikal LA; Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt.
  • Teleb M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt.
Eur J Med Chem ; 252: 115272, 2023 Apr 05.
Article em En | MEDLINE | ID: mdl-36966652
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Tipo de estudo: Guideline Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Tipo de estudo: Guideline Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article