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Structure-Activity Relationships of Truncated 1'-Homologated Carbaadenosine Derivatives as New PPARγ/δ Ligands: A Study on Sugar Puckering Affecting Binding to PPARs.
Hyun, Young Eum; An, Seungchan; Kim, Minjae; Park, In Guk; Yoon, Sanghee; Javaid, Hafiz Muhammad Ahmad; Vu, Thi Ngoc Lan; Kim, Gyudong; Choi, Hongseok; Lee, Hyuk Woo; Noh, Minsoo; Huh, Joo Young; Choi, Sun; Kim, Hong-Rae; Jeong, Lak Shin.
Afiliação
  • Hyun YE; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
  • An S; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
  • Kim M; Natural Products Research Institute, Seoul National University, Seoul 08826, Korea.
  • Park IG; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
  • Yoon S; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
  • Javaid HMA; Natural Products Research Institute, Seoul National University, Seoul 08826, Korea.
  • Vu TNL; Global AI Drug Discovery Center, College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea.
  • Kim G; College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju 61186, Korea.
  • Choi H; Global AI Drug Discovery Center, College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea.
  • Lee HW; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
  • Noh M; College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju 61186, Korea.
  • Huh JY; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
  • Choi S; Future Medicine Co., Ltd., Seongnam 13449, Gyeonggi-do, Korea.
  • Kim HR; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
  • Jeong LS; Natural Products Research Institute, Seoul National University, Seoul 08826, Korea.
J Med Chem ; 66(7): 4961-4978, 2023 04 13.
Article em En | MEDLINE | ID: mdl-36967575
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: PPAR delta / PPAR gama Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: PPAR delta / PPAR gama Idioma: En Ano de publicação: 2023 Tipo de documento: Article