What drives CAR-T emergent cytopenia?
Br J Haematol
; 202(2): 213-214, 2023 07.
Article
em En
| MEDLINE
| ID: mdl-37009828
ABSTRACT
Prolonged cytopenia after CAR-T cell therapy is an acknowledged problem. At present, the causes and implications of prolonged cytopenia are unclear. The paper by Kitamura et al identified that prolonged cytopenia is associated with alterations in the bone marrow niche identified before CAR-T therapy, indicating a potential predictor of this serious side-effect of treatment. Commentary on Kitamura et al. Bone marrow microenvironment disruption and sustained inflammation with prolonged haematologic toxicity after CAR T-cell therapy? Br J Haematol 2023;202294-307.
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Base de dados:
MEDLINE
Assunto principal:
Receptores de Antígenos Quiméricos
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article