Fate mapping RNA-sequencing reveal Malat1 regulates Sca1<sup>+</sup> progenitor cells to vascular smooth muscle cells transition in vascular remodeling.

Lyu, Lingxia; Li, Zhoubin; Wen, Zuoshi; He, Yongchun; Wang, Xuliang; Jiang, Liujun; Zhou, Xuhao; Huang, Chengchen; Wu, Yutao; Chen, Ting; Guo, Xiaogang

Fate mapping RNA-sequencing reveal Malat1 regulates Sca1⁺ progenitor cells to vascular smooth muscle cells transition in vascular remodeling.

Lyu, Lingxia; Li, Zhoubin; Wen, Zuoshi; He, Yongchun; Wang, Xuliang; Jiang, Liujun; Zhou, Xuhao; Huang, Chengchen; Wu, Yutao; Chen, Ting; Guo, Xiaogang.

Afiliação

Lyu L; Department of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Li Z; Department of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Wen Z; Department of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
He Y; Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Wang X; Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Jiang L; Department of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Zhou X; Department of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Huang C; Department of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Wu Y; Department of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Chen T; Department of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. ct010151452@zju.edu.cn.
Guo X; Alibaba-Zhejiang University Joint Research Center of Future Digital Healthcare, Hangzhou, China. ct010151452@zju.edu.cn.

Cell Mol Life Sci ; 80(5): 118, 2023 Apr 06.

Article em En | MEDLINE | ID: mdl-37022488

Assuntos

RNA Longo não Codificante; Ataxias Espinocerebelares; Doenças Vasculares; Animais; Camundongos; Células Cultivadas; Modelos Animais de Doenças; Músculo Liso Vascular; Miócitos de Músculo Liso/metabolismo; RNA Longo não Codificante/genética; RNA Longo não Codificante/metabolismo; Ataxias Espinocerebelares/metabolismo; Células-Tronco/metabolismo; Doenças Vasculares/metabolismo; Remodelação Vascular/genética

Palavras-chave

Arteriovenous fistula; Malat1; Sca1+ cells; Single-cell sequencing; Vascular remodeling

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças Vasculares / Ataxias Espinocerebelares / RNA Longo não Codificante Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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