A PET Fluorescent Probe for Dynamic Pd2+ Tracking with Imaging Applications in the Nanofiber and Living Cells.
Molecules
; 28(7)2023 Mar 29.
Article
em En
| MEDLINE
| ID: mdl-37049828
ABSTRACT
Constructed on the moiety of a lactam screw ring, a near-infrared fluorescent probe RCya for Pd2+ was designed under the PET mechanism and synthesized by incorporating 2,4-dihydroxybenzaldehyde as the recognition group. Dynamic detection of aqueous Pd2+ by the probe RCya could be accomplished through ion competition, linear response, fluorescence-pH/time stabilities, and other optical tests. Moreover, the high selectivity, low cytotoxicity, cell permeability, and lysosome accumulation properties of RCya enabled the imaging applications on solid-state RCya-PAN composite nanofibers and in living cells. The recognition mechanism of probe RCya toward Pd2+ was further studied through simulation calculation and MS analysis.
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Base de dados:
MEDLINE
Assunto principal:
Nanofibras
/
Corantes Fluorescentes
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article