Treatment of melanoma with dendritic cell vaccines and immune checkpoint inhibitors: A mathematical modeling study.

Xue, Ling; Zhang, Hongyu; Zheng, Xiaoming; Sun, Wei; Lei, Jinzhi

Xue, Ling; Zhang, Hongyu; Zheng, Xiaoming; Sun, Wei; Lei, Jinzhi.

Afiliação

Xue L; College of Intelligent Systems Science and Engineering, Harbin Engineering University, Harbin, Heilongjiang, 150001, China; College of Mathematical Sciences, Harbin Engineering University, Harbin, Heilongjiang, 150001, China.
Zhang H; College of Intelligent Systems Science and Engineering, Harbin Engineering University, Harbin, Heilongjiang, 150001, China; College of Mathematical Sciences, Harbin Engineering University, Harbin, Heilongjiang, 150001, China.
Zheng X; Department of Mathematics, Central Michigan University, Mount Pleasant, MI 48859, United States of America.
Sun W; College of Intelligent Systems Science and Engineering, Harbin Engineering University, Harbin, Heilongjiang, 150001, China; College of Mathematical Sciences, Harbin Engineering University, Harbin, Heilongjiang, 150001, China. Electronic address: sunweihit@hrbeu.edu.cn.
Lei J; School of Mathematical Sciences, Center for Applied Mathematics, Tiangong University, Tianjin, 300387, China. Electronic address: jzlei@tiangong.edu.cn.

J Theor Biol ; 568: 111489, 2023 07 07.

Article em En | MEDLINE | ID: mdl-37054970

Assuntos

Vacinas Anticâncer; Melanoma; Vacinas; Humanos; Inibidores de Checkpoint Imunológico; Células Dendríticas; Melanoma/terapia; Imunoterapia/métodos; Modelos Teóricos; Vacinas Anticâncer/uso terapêutico

Palavras-chave

Combined therapy; Dendritic cell vaccines; Hopf bifurcation; Immune checkpoint inhibitors; Melanoma; Tumor-immune system

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas / Vacinas Anticâncer / Melanoma Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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