Chiral separation of racemic closantel and ultratrace detection of its enantiomers in bacteria by enhanced liquid chromatography-tandem mass spectrometry combined with postcolumn infusion of ammonia.

Ding, Tongyan; Liu, Longyun; Liu, Yilei; Jiang, Shuanghui; Guo, Wenying; Liu, Rong; He, Limin

Ding, Tongyan; Liu, Longyun; Liu, Yilei; Jiang, Shuanghui; Guo, Wenying; Liu, Rong; He, Limin.

Afiliação

Ding T; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural University, Guangzhou, 510642, China; National Reference Laboratory of Veterinary Drug Residues, College of Veterinary Medicine, South China Agricultural University (SCAU), Gua
Liu L; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural University, Guangzhou, 510642, China.
Liu Y; National Reference Laboratory of Veterinary Drug Residues, College of Veterinary Medicine, South China Agricultural University (SCAU), Guangzhou, 510642, China.
Jiang S; National Reference Laboratory of Veterinary Drug Residues, College of Veterinary Medicine, South China Agricultural University (SCAU), Guangzhou, 510642, China.
Guo W; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural University, Guangzhou, 510642, China.
Liu R; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural University, Guangzhou, 510642, China.
He L; Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural University, Guangzhou, 510642, China; National Reference Laboratory of Veterinary Drug Residues, College of Veterinary Medicine, South China Agricultural University (SCAU), Gua

J Chromatogr A ; 1698: 464001, 2023 Jun 07.

Article em En | MEDLINE | ID: mdl-37087856

Assuntos

Amônia; Espectrometria de Massas em Tandem; Espectrometria de Massas em Tandem/métodos; Cromatografia Líquida/métodos; Antibacterianos/toxicidade; Bactérias; Cromatografia Líquida de Alta Pressão/métodos

Palavras-chave

Bacteria; Closantel; Enantioseparation; Liquid chromatography-tandem mass spectrometry combined with postcolumn infusion; Ultratrace analysis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espectrometria de Massas em Tandem / Amônia Tipo de estudo: Diagnostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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