Genipin Inhibits the Development of Osteosarcoma through PI3K/AKT Signaling Pathway.

Huang, Xiongjie; Jiwa, Habu; Xu, Jingtao; Zhang, Jun; Huang, Yanran; Luo, Xiaoji

Huang, Xiongjie; Jiwa, Habu; Xu, Jingtao; Zhang, Jun; Huang, Yanran; Luo, Xiaoji.

Afiliação

Huang X; Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Jiwa H; Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Xu J; Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Zhang J; Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Huang Y; Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Luo X; Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.

Curr Pharm Des ; 29(16): 1300-1310, 2023.

Article em En | MEDLINE | ID: mdl-37157220

Assuntos

Neoplasias Ósseas; Iridoides; Osteossarcoma; Animais; Humanos; Apoptose; Neoplasias Ósseas/tratamento farmacológico; Neoplasias Ósseas/patologia; Linhagem Celular Tumoral; Movimento Celular; Proliferação de Células; Osteossarcoma/tratamento farmacológico; Osteossarcoma/patologia; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Qualidade de Vida; Transdução de Sinais; Iridoides/farmacologia

Palavras-chave

Genipin; PI3K/AKT signaling; apoptosis; migration; osteosarcoma; proliferation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Osteossarcoma / Iridoides Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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