Zinc oxide nanoparticles have biphasic roles on Mycobacterium-induced inflammation by activating autophagy and ferroptosis mechanisms in infected macrophages.

Geng, SiJia; Hao, PengFei; Wang, Di; Zhong, Pengfei; Tian, Fangfang; Zhang, Rui; Qiao, Juan; Qiu, Xiaochen; Bao, Pengtao

Geng, SiJia; Hao, PengFei; Wang, Di; Zhong, Pengfei; Tian, Fangfang; Zhang, Rui; Qiao, Juan; Qiu, Xiaochen; Bao, Pengtao.

Afiliação

Geng S; Graduate School, Hebei North University, Zhangjiakou, Hebei Province, 075000, PR China.
Hao P; Graduate School, Hebei North University, Zhangjiakou, Hebei Province, 075000, PR China.
Wang D; The Eighth Medical Center of Chinese PLA General Hospital, Pulmonary and Critical Care Medicine Faculty of Chinese PLA General Hospital, Beijing, 100093, PR China.
Zhong P; Graduate School, Hebei North University, Zhangjiakou, Hebei Province, 075000, PR China.
Tian F; The Eighth Medical Center of Chinese PLA General Hospital, Pulmonary and Critical Care Medicine Faculty of Chinese PLA General Hospital, Beijing, 100093, PR China.
Zhang R; The Eighth Medical Center of Chinese PLA General Hospital, Pulmonary and Critical Care Medicine Faculty of Chinese PLA General Hospital, Beijing, 100093, PR China.
Qiao J; The Eighth Medical Center of Chinese PLA General Hospital, Pulmonary and Critical Care Medicine Faculty of Chinese PLA General Hospital, Beijing, 100093, PR China. Electronic address: keyan30908@163.com.
Qiu X; Department of General Surgery, The Eighth Medical Center of Chinese PLA General Hospital, Beijing, 100093, PR China. Electronic address: qiuxiaochen1987@163.com.
Bao P; The Eighth Medical Center of Chinese PLA General Hospital, Pulmonary and Critical Care Medicine Faculty of Chinese PLA General Hospital, Beijing, 100093, PR China. Electronic address: bao03@163.com.

Microb Pathog ; 180: 106132, 2023 Jul.

Article em En | MEDLINE | ID: mdl-37201638

Assuntos

Ferroptose; Mycobacterium tuberculosis; Nanopartículas; Óxido de Zinco; Camundongos; Animais; Óxido de Zinco/farmacologia; Vacina BCG; Autofagia; Antibacterianos/farmacologia; Inflamação

Palavras-chave

Autophagy; Cytotoxicity; Ferroptosis; Mycobacterium tuberculosis; Pulmonary tuberculosis; Zinc oxide nanoparticles

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Óxido de Zinco / Nanopartículas / Ferroptose / Mycobacterium tuberculosis Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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